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擅長(zhǎng)

磨玻璃結(jié)節(jié)，磨玻璃影，GGN,GGO，肺部結(jié)節(jié)以及早期肺癌的鑒別診斷與微創(chuàng)治療，肺部結(jié)節(jié)（包括實(shí)性結(jié)節(jié)以及亞實(shí)性結(jié)節(jié)）的單孔微創(chuàng)外科治療，疑難或復(fù)雜胸部外科手術(shù)，胸部第二次手術(shù)，靶向治療或免疫治療后降期的肺癌手術(shù)治療，并擅長(zhǎng)肺癌綜合治療（包括靶向治療，化療，免疫治療），以及腫瘤療效影像學(xué)評(píng)估。擅長(zhǎng)氣管腫瘤、氣管狹窄、氣管食管瘺的外科治療，擅長(zhǎng)胸腔、胸壁巨大腫瘤的外科治療，擅長(zhǎng)胸腺腫瘤（胸腺瘤，復(fù)發(fā)性胸腺瘤，胸腺癌）、縱隔神經(jīng)源性腫瘤，縱隔畸胎瘤的外科治療，特別是早期胸腺瘤的單孔胸腔鏡微創(chuàng)外科治療。肺移植：間質(zhì)性肺炎，特發(fā)性肺纖維化，COPD（重度肺氣腫），肺動(dòng)脈高壓，肺淋巴管平滑肌瘤病等。胸膜胸壁疾病的外科治療：胸壁腫瘤，胸膜腫瘤，惡性胸膜間皮瘤等。

簡(jiǎn)介

謝冬，上海市肺科醫(yī)院胸外科行政副主任，主任醫(yī)師，教授，博士生導(dǎo)師，博士后合作導(dǎo)師，IASLC （國(guó)際肺癌研究協(xié)會(huì)）會(huì)員，AME學(xué)術(shù)沙龍委員，EACTS（歐洲胸心血管外科學(xué)會(huì)）會(huì)員，ESTS（歐洲胸外科醫(yī)師協(xié)會(huì)）會(huì)員，STS（美國(guó)胸外科醫(yī)師協(xié)會(huì)）會(huì)員。2013-2014年至美國(guó)Mayo clinic（梅奧中心）胸外科及癌癥中心進(jìn)修，個(gè)人年手術(shù)量1500余例，主要研究方向：基于臨床大數(shù)據(jù)的肺癌精準(zhǔn)治療，肺癌人工智能相關(guān)研究，第一作者或通訊作者，在JTO，NC，EJC，JTCVS，ATS，Acta Pharmacol Sin,Acta Biomater等雜志發(fā)表SCI論文60余篇，國(guó)際會(huì)議發(fā)言10余次。擅長(zhǎng)肺部磨玻璃結(jié)節(jié)，磨玻璃影，GGN，GGO，肺部結(jié)節(jié)以及早期肺癌的微創(chuàng)治療，肺部結(jié)節(jié)（包括實(shí)性結(jié)節(jié)以及亞實(shí)性結(jié)節(jié)）的單孔微創(chuàng)外科治療，并擅長(zhǎng)肺癌、胸腺腫瘤（胸腺瘤，胸腺囊腫，胸腺癌）、縱隔腫瘤的綜合治療。

社會(huì)任職

中國(guó)醫(yī)促會(huì)加速康復(fù)外科學(xué)分會(huì)——胸外科康復(fù)學(xué)組副組長(zhǎng)
中國(guó)胸心血管外科臨床雜志青年編委
中國(guó)醫(yī)促會(huì)胸外科分會(huì)青年委員
中國(guó)醫(yī)師協(xié)會(huì)醫(yī)學(xué)科普分會(huì)腫瘤科普專業(yè)委員會(huì)委員
中國(guó)醫(yī)藥教育協(xié)會(huì)肺癌醫(yī)學(xué)教育委員會(huì)常委
中國(guó)醫(yī)師協(xié)會(huì)上海市胸外科分會(huì)委員
CSCO微創(chuàng)腫瘤學(xué)分會(huì)委員
上海市醫(yī)學(xué)會(huì)腫瘤靶分子委員會(huì)青年委員
JTO、JTD等雜志審稿專家
STS美國(guó)胸外科醫(yī)師協(xié)會(huì)年會(huì)審稿專家

獲獎(jiǎng)榮譽(yù)

上海市浦江人才
上海市“醫(yī)苑新星”杰出青年醫(yī)學(xué)人才
獲得上海市肺科醫(yī)院“信賴的好醫(yī)生”稱號(hào)
2016年獲同濟(jì)大學(xué)十佳醫(yī)務(wù)青年
2016年獲上海市醫(yī)務(wù)職工科技創(chuàng)新“星光計(jì)劃”三等獎(jiǎng)（第一完成人）
獲得好大夫在線2016，2017，2019年，2020年度好大夫稱號(hào)
2015年“不切除肺的支氣管節(jié)段切除治療支氣管良惡性疾病”獲上海市肺科醫(yī)院臨床成果三等獎(jiǎng)（第一完成人）
2015年“磨玻璃影早期肺癌的微創(chuàng)外科治療”獲上海市肺科醫(yī)院臨床成果一等獎(jiǎng)

科研成果

主持國(guó)自然，市科委課題等十余項(xiàng),個(gè)人獲資助400余萬(wàn)
在國(guó)內(nèi)外胸外科雜志發(fā)表論文160余篇，其中第一作者或通訊作者發(fā)表SCI論文60余篇，中華雜志30余篇。谷歌學(xué)術(shù)累計(jì)他引 3300 余次，H-index 為 32。主編《遇到磨玻璃結(jié)節(jié)莫驚慌》，《肺癌新輔助治療進(jìn)展》,《胸部腫瘤的精準(zhǔn)治療》,《肺移植新進(jìn)展》四本專著，參編專著《肺外科學(xué)》、《Atlas of Uniportal VATS》、《腫瘤外科手術(shù)彩色圖譜》等10本。
實(shí)用新型專利獲得2項(xiàng)。
部分論文如下（第一作者或通訊作者）
1. Xie, D., Marks, R., Zhang, M., Jiang, G., Jatoi, A., Garces, Y. I., Mansfield, A., Molina, J. & Yang, P. (2015) Nomograms Predict Overall Survival for Patients with Small-Cell Lung Cancer Incorporating Pretreatment Peripheral Blood Markers, J Thorac Oncol. 10, 1213-20.
2. Chen, Y., Yuan, Z. C., Sun, W. Y., Shafiq, M., Zhu, J., Chen, J. F., Tang, H., Hu, L., Lin, W. K., Zeng, Y. X., Wang, L., Zhang, L., She, Y. L., Zheng, H., Zhao, G. F., Xie, D., Mo, X. M. & Chen, C. (2023) Vascular Endothelial Growth Factor-Recruiting Nanofiber Bandages Promote Multifunctional Skin Regeneration via Improved Angiogenesis and Immunomodulation, Advanced Fiber Materials. 5, 327-348.
3. Zhong, Y., Cai, C., Chen, T., Gui, H., Deng, J., Yang, M., Yu, B., Song, Y., Wang, T., Sun, X., Shi, J., Chen, Y., Xie, D., Chen, C. & She, Y. (2023) PET/CT based cross-modal deep learning signature to predict occult nodal metastasis in lung cancer, Nat Commun. 14, 7513.
4. Tao, C., Ren, Q., Qiu, P., Niu, S. N., Chen, Z. G., Li, K., Xie, D., Yu, N. & Wen, M. (2024) Design of multifunctional theranostic nanoplatforms with glutathione-triggered H2S 2 S generation and H2S-activitated 2 S-activitated multi-modal therapy, Chemical Engineering Journal. 495.
5. Li, K., Wu, L., Wang, H., Fu, Z., Gao, J., Liu, X., Fan, Y., Qin, X., Ni, D., Wang, J. & Xie, D. (2024) Apoptosis and cuproptosis Co-activated Copper-based metal-organic frameworks for cancer therapy, J Nanobiotechnology. 22, 546.
Zhong, Y., Cai, C., Chen, T., Gui, H., Chen, C., Deng, J., Yang, M., Yu, B., Song, Y., Wang, T., Chen, Y., Shi, H., 6.Xie, D., Chen, C. & She, Y. (2024) PET/CT-based deep learning grading signature to optimize surgical decisions for clinical stage I invasive lung adenocarcinoma and biologic basis under its prediction: a multicenter study, Eur J Nucl Med Mol Imaging. 51, 521-534.
7. She, Y., Li, S., Deng, J., Ren, Y., Zhao, M., Zhong, Y., He, Y., Chen, Q., Zhao, D., Zhu, Y., Hou, L., Wu, C., Xie, D. & Chen, C. (2022) Clinicopathologic characteristics and prognostic impact of atypical EGFR mutations in completely resected lung adenocarcinoma, Eur J Cancer. 177, 53-62.
8. Hao, B. B., Ma, K., Xu, J. Y., Fan, R. F., Zhao, W. S., Jia, X. L., Zhai, L. H., Lee, S., Xie, D. & Tan, M. J. (2024) Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations, Acta Pharmacol Sin. 45, 1305-1315.
9. Shi, Y., Li, C., Zhang, X., Peng, C., Sun, P., Zhang, Q., Wu, L., Ding, Y., Xie, D., Xu, Z. & Zhu, W. (2024) D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer, Brief Bioinform. 25.
10. Lin, J. W., Zhou, Y., Xiao, H. P., Wu, L. L., Li, P. C., Huang, M. D., Xie, D., Xu, P., Li, X. X. & Li, Z. X. (2024) Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis, Chemical Science.
11. Yang, M. L., Sun, W. Y., Wang, L., Tang, H., Xu, X., Yang, L. W., Ni, J. J., Zheng, K. E., Jiang, X., Xu, W. W., Zhao, G. F., She, Y. L., Zhang, L., Xie, D. & Chen, C. (2022) Curcumin loaded polycaprolactone scaffold capable of anti-inflammation to enhance tracheal cartilage regeneration, Materials & Design. 224.
12. Xie, D., Deng, J., Gonzalez-Rivas, D., Zhu, Y., Jiang, L., Jiang, G. & Chen, C. (2021) Comparison of video-assisted thoracoscopic surgery with thoracotomy in bronchial sleeve lobectomy for centrally located non-small cell lung cancer, J Thorac Cardiovasc Surg. 161, 403-413.e2.
13. Wu, L. L., Qiu, L. H., Chen, X., Yu, W. J., Li, C. W., Qian, J. Y., Liang, S. H., Lin, P., Long, H., Zhang, L. J., Li, Z. X., Li, K., Jiang, F., Ma, G. W. & Xie, D. (2023) Reconsidering N component of cancer staging for T1-2N0-2M0 small-cell lung cancer: a retrospective study based on multicenter cohort, Respir Res. 24, 168.
14. Qian, J. Y., Hao, Y., Yu, H. H., Wu, L. L., Liu, Z. Y., Peng, Q., Li, Z. X., Li, K., Liu, Y., Wang, R. R. & Xie, D. (2023) A Novel Systematic Oxidative Stress Score Predicts the Survival of Patients with Early-Stage Lung Adenocarcinoma, Cancers (Basel). 15.
15. Wu, L. L., Qian, J. Y., Li, C. W., Zhang, Y., Lin, W. K., Li, K., Li, Z. X. & Xie, D. (2022) The Clinical and Prognostic Characteristics of Primary Salivary Gland-Type Carcinoma in the Lung: A Population-Based Study, Cancers (Basel). 14.
16. Wu, L. L., Chen, W. T., Li, C. W., Song, S. H., Xu, S. Q., Wan, S. P., Liu, Z. Y., Lin, W. K., Li, K., Li, Z. X. & Xie, D. (2022) The Construction and Validation of Nomogram to Predict the Prognosis with Small-Cell Lung Cancer Followed Surgery, Cancers (Basel). 14.
17. Gao, J., Zhang, L., Li, Z., Wang, F., Qiu, L., Dou, X., Li, C., Zhu, Y., Ma, G., Jiang, G., Xie, D. & Chen, C. (2021) UniPortal thoracoscopic pneumonectomy does not compromise perioperative and long-term survival in patients with NSCLC: A retrospective, multicenter, and propensity score matching study, Lung Cancer. 159, 135-144.
18. Deng, J., Zhao, M., Wang, T., She, Y., Wu, J., E, H., Gao, J., Sun, X., Jiang, G., Zhu, Y., Xie, D. & Chen, C. (2020) A modified T categorization for part-solid lesions in Chinese patients with clinical stage I Non-small cell lung cancer, Lung Cancer. 145, 33-39.
19. Deng, J., She, Y., Yang, M., Zhang, L., Xie, D. & Chen, C. (2020) Radiomics: a potential biomarker for N2 malignancy in clinical stage I lung adenocarcinoma, Transl Lung Cancer Res. 9, 1623-1624.
20. Xie, D., Wang, T. T., Huang, S. J., Deng, J. J., Ren, Y. J., Yang, Y., Wu, J. Q., Zhang, L., Fei, K., Sun, X. W., She, Y. L. & Chen, C. (2020) Radiomics nomogram for prediction disease-free survival and adjuvant chemotherapy benefits in patients with resected stage I lung adenocarcinoma, Transl Lung Cancer Res. 9, 1112-1123.
21. Yang, M., She, Y., Deng, J., Wang, T., Ren, Y., Su, H., Wu, J., Sun, X., Jiang, G., Fei, K., Zhang, L., Xie, D. & Chen, C. (2019) CT-based radiomics signature for the stratification of N2 disease risk in clinical stage I lung adenocarcinoma, Transl Lung Cancer Res. 8, 876-885.
22.Shen Y, Yu N, Zhao W, Niu S, Qiu P, Zeng H, Chen Z, Men W, Xie D.M1-macrophage membrane-camouflaged nanoframeworks activate multiple immunity via calcium overload and photo-sonosensitization.Biomaterials,2025,DOI: 10.1016/j.biomaterials.2025.123287.
23.Lin W, Tang H, Cao R, Chen J, Wang L, She Y, Zhang L, Chen Y, Pan Z, Bai Q, Zhao D, Yang M, Zhao G, Sun W, Xie D, Chen C.3D-printed Engineered Trachea Functionalized by Diverse Extracellular Matrix Particles.Adv Healthc Mater,2025,DOI: 10.1002/adhm.202500124.
24.Yi C, Bian D, Wang J, Hu S, Sun L, Yan Y, Wang S, Shen Z, Yu H, Yang Y, Zhou Y, Liu X, Song N, Zhu Y, Zhao D, Jiang G, Duan L, He W, Xie D, Dai J, Zhang L, Zhang P.: Anti-PD1 based precision induction therapy in unresectable stage III non-small cell lung cancer: a phase II umbrella clinical trial. Nat Commun 2025, 16(1):1932.
25.Wen M, Qiu P, Meng J, Zhao W, Wang X, Niu S, Tao C, Yu N, Chen Z, Xie D: Multifunctional nanozymes for sonodynamic-enhanced immune checkpoint blockade therapy by inactivating PI3K/AKT signal pathway. Biomaterials 2025, 318:123125.
26.Zhou LQ, Li K, Liu YY, Zhang RJ, Yao YC, Chen QQ, Xie D, Zhang XJ: Living Cell-Derived Intelligent Nanobots for Precision Oncotherapy. Advanced Functional Materials 2024, 34(10).
27.Zhong Y, Cai C, Chen T, Gui H, Chen C, Deng J, Yang M, Yu B, Song Y, Wang T et al: PET/CT-based deep learning grading signature to optimize surgical decisions for clinical stage I invasive lung adenocarcinoma and biologic basis under its prediction: a multicenter study. Eur J Nucl Med Mol Imaging 2024, 51(2):521-534.
28.Lin JW, Zhou Y, Xiao HP, Wu LL, Li PC, Huang MD, Xie D, Xu P, Li XX, Li ZX: Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis. Chem Sci 2024, 15(37):15367-15376.

部分中文文章：
1.謝冬,陳昶，王海峰，等. 閉合性氣管支氣管損傷15例. 中華胸心血管外科雜志,2016,32(2)94-98.
2. 包敏偉,謝冬,費(fèi)苛，姜格寧，等. 116例胸腺囊腫的外科治療. 中華胸心血管外科雜志,2016,32(1):14-17.
3. 謝冬, 包敏偉,謝惠康，等.113例縱隔畸胎瘤的外科治療. 中華胸心血管外科雜志,2016，32(3)：132-135.
4. 周琪,謝冬,費(fèi)苛,姜格寧. 心包切開(kāi)術(shù)后綜合征診治進(jìn)展.中國(guó)胸心血管外科臨床雜志. 2017, 24(4): 306-309.
5.謝冬,陳昶,朱余明,姜格寧.單孔胸腔鏡手術(shù)的現(xiàn)狀與展望.中華腔鏡外科雜志,2016,9(2):4-7.
6.謝冬,陳昶,姜格寧. 肺癌外科手術(shù)切口的演變與發(fā)展趨勢(shì),中國(guó)肺癌雜志, ,2016,(6):343-346.
7. 謝冬,戴潔,楊平,姜格寧.肺癌精準(zhǔn)外科發(fā)展現(xiàn)狀與展望, 中華實(shí)驗(yàn)外科雜志,2016,(8):1889-1892.
8. 厲逑元, 謝冬, 姜格寧.普胸外科手術(shù)風(fēng)險(xiǎn)預(yù)測(cè)模型的現(xiàn)狀與進(jìn)展,中華胸心血管外科雜志，2016,(9):561-564,568.
9.謝冬, 姜格寧. 胸鎖關(guān)節(jié)感染的外科治療，中華胸心血管外科雜志,2016,, 32(8):506-508.
10.謝冬,金宇星,王海峰等. 59例支氣管結(jié)石病的外科治療. 中華胸心血管外科雜志,2015,31(4):217-220.
11. 謝冬, 姜格寧，趙德平，等. 單孔全胸腔鏡治療中央型肺部腫瘤5例. 中華胸心血管外科雜志, 2015,31(3):177-178.
12.謝冬,尤小芳,謝惠康,陳曉峰,徐志飛,姜格寧, 陳昶,周曉,丁嘉安. 18例支氣管內(nèi)型錯(cuò)構(gòu)瘤的臨床分析. 中華胸心血管外科雜志,2012,28(3):167-168.
13. 謝冬,姜格寧,徐志飛等.插管后氣管狹窄的外科治療進(jìn)展. 中華胸心血管外科雜志, 2013, 29(3):180-182.
14.謝冬,姜格寧,費(fèi)苛,等. 肺切除術(shù)后支氣管胸膜瘺的治療進(jìn)展. 中華胸心血管外科雜志, 2013, 29(8):502-504.
15.謝冬,姜格寧,陳曉峰，等.114例肺隔離癥的外科治療. 中華外科雜志, 2013，51(9):861-862.
16. 謝冬,費(fèi)苛,姜格寧，等. 不切除肺的支氣管節(jié)段切除術(shù)23例報(bào)道. 中華外科雜志, 2013，51(10):942-944.