謝冬

寄語

全心全意的對待每一個患者 達成我們的信念和使命
得病的你并不孤獨，因為有很多人在關心你，因為這是大家的事情，那么---請讓我們大家來幫助你，而你只要勇敢的面對就行了。

專業(yè)擅長

磨玻璃結節(jié)，磨玻璃影，GGN,GGO，肺部結節(jié)以及早期肺癌的鑒別診斷與微創(chuàng)治療，肺部結節(jié)（包括實性結節(jié)以及亞實性結節(jié)）的單孔微創(chuàng)外科治療，疑難或復雜胸部外科手術，胸部第二次手術，靶向治療或免疫治療后降期的肺癌手術治療，并擅長肺癌綜合治療（包括靶向治療，化療，免疫治療），以及腫瘤療效影像學評估。擅長氣管腫瘤、氣管狹窄、氣管食管瘺的外科治療，擅長胸腔、胸壁巨大腫瘤的外科治療，擅長胸腺腫瘤（胸腺瘤，復發(fā)性胸腺瘤，胸腺癌）、縱隔神經(jīng)源性腫瘤，縱隔畸胎瘤的外科治療，特別是早期胸腺瘤的單孔胸腔鏡微創(chuàng)外科治療。肺移植：間質性肺炎，特發(fā)性肺纖維化，COPD（重度肺氣腫），肺動脈高壓，肺淋巴管平滑肌瘤病等。胸膜胸壁疾病的外科治療：胸壁腫瘤，胸膜腫瘤，惡性胸膜間皮瘤等。

我的團隊

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  金海龍  副主任醫(yī)師

  吳淞中心醫(yī)院  胸外科

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  李昆  主治醫(yī)師

  上海市肺科醫(yī)院  胸外科

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  朱巍  主治醫(yī)師

  上海市肺科醫(yī)院  影像科

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  張磊  醫(yī)生助手

    

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  陳愛華  醫(yī)生助手

    

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  王禮平  醫(yī)生助手

    

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  陳恒琴  醫(yī)生助手

    

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  王瑾  醫(yī)生助手

    

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  王靜  醫(yī)生助手

    

個人簡介

謝冬，上海市肺科醫(yī)院胸外科行政副主任，主任醫(yī)師，教授，博士生導師，博士后合作導師，IASLC （國際肺癌研究協(xié)會）會員，AME學術沙龍委員，EACTS（歐洲胸心血管外科學會）會員，ESTS（歐洲胸外科醫(yī)師協(xié)會）會員，STS（美國胸外科醫(yī)師協(xié)會）會員。2013-2014年至美國Mayo clinic（梅奧中心） 胸外科及癌癥中心進修，個人年手術量1500余例，主要研究方向：基于臨床大數(shù)據(jù)的肺癌精準治療，肺癌人工智能相關研究，第一作者或通訊作者，在JTO，NC，EJC，JTCVS，ATS，Acta Pharmacol Sin,Acta Biomater等雜志發(fā)表SCI論文60余篇，國際會議發(fā)言10余次。擅長肺部磨玻璃結節(jié)，磨玻璃影，GGN，GGO，肺部結節(jié)以及早期肺癌的微創(chuàng)治療，肺部結節(jié)（包括實性結節(jié)以及亞實性結節(jié)）的單孔微創(chuàng)外科治療，并擅長肺癌、胸腺腫瘤（胸腺瘤，胸腺囊腫，胸腺癌）、縱隔腫瘤的綜合治療。

社會任職

中國醫(yī)促會加速康復外科學分會——胸外科康復學組副組長中國胸心血管外科臨床雜志青年編委中國醫(yī)促會胸外科分會青年委員中國醫(yī)師協(xié)會醫(yī)學科普分會腫瘤科普專業(yè)委員會委員中國醫(yī)藥教育協(xié)會肺癌醫(yī)學教育委員會常委中國醫(yī)師協(xié)會上海市胸外科分會委員CSCO微創(chuàng)腫瘤學分會委員上海市醫(yī)學會腫瘤靶分子委員會青年委員JTO、JTD等雜志審稿專家STS美國胸外科醫(yī)師協(xié)會年會審稿專家

獲獎榮譽

上海市浦江人才上海市“醫(yī)苑新星”杰出青年醫(yī)學人才獲得上海市肺科醫(yī)院“信賴的好醫(yī)生”稱號2016年獲同濟大學十佳醫(yī)務青年2016年獲上海市醫(yī)務職工科技創(chuàng)新“星光計劃”三等獎（第一完成人）獲得好大夫在線2016，2017，2019年，2020年度好大夫稱號2015年“不切除肺的支氣管節(jié)段切除治療支氣管良惡性疾病”獲上海市肺科醫(yī)院 臨床成果三等獎（第一完成人）2015年“磨玻璃影早期肺癌的微創(chuàng)外科治療”獲上海市肺科醫(yī)院 臨床成果一等獎

科研成果

主持國自然，市科委課題等十余項,個人獲資助400余萬在國內外胸外科雜志發(fā)表論文160余篇，其中第一作者或通訊作者發(fā)表SCI論文60余篇，中華雜志30余篇。谷歌學術累計他引 3300 余次，H-index 為 32。主編《遇到磨玻璃結節(jié)莫驚慌》，《肺癌新輔助治療進展》,《胸部腫瘤的精準治療》,《肺移植新進展》四本專著，參編專著《肺外科學》、《Atlas of Uniportal VATS》、《腫瘤外科手術彩色圖譜》等10本。實用新型專利獲得2項。部分論文如下（第一作者或通訊作者）1. Xie, D., Marks, R., Zhang, M., Jiang, G., Jatoi, A., Garces, Y. I., Mansfield, A., Molina, J. & Yang, P. (2015) Nomograms Predict Overall Survival for Patients with Small-Cell Lung Cancer Incorporating Pretreatment Peripheral Blood Markers, J Thorac Oncol. 10, 1213-20.2. Chen, Y., Yuan, Z. C., Sun, W. Y., Shafiq, M., Zhu, J., Chen, J. F., Tang, H., Hu, L., Lin, W. K., Zeng, Y. X., Wang, L., Zhang, L., She, Y. L., Zheng, H., Zhao, G. F., Xie, D., Mo, X. M. & Chen, C. (2023) Vascular Endothelial Growth Factor-Recruiting Nanofiber Bandages Promote Multifunctional Skin Regeneration via Improved Angiogenesis and Immunomodulation, Advanced Fiber Materials. 5, 327-348.3. Zhong, Y., Cai, C., Chen, T., Gui, H., Deng, J., Yang, M., Yu, B., Song, Y., Wang, T., Sun, X., Shi, J., Chen, Y., Xie, D., Chen, C. & She, Y. (2023) PET/CT based cross-modal deep learning signature to predict occult nodal metastasis in lung cancer, Nat Commun. 14, 7513.4. Tao, C., Ren, Q., Qiu, P., Niu, S. N., Chen, Z. G., Li, K., Xie, D., Yu, N. & Wen, M. (2024) Design of multifunctional theranostic nanoplatforms with glutathione-triggered H2S 2 S generation and H2S-activitated 2 S-activitated multi-modal therapy, Chemical Engineering Journal. 495.5. Li, K., Wu, L., Wang, H., Fu, Z., Gao, J., Liu, X., Fan, Y., Qin, X., Ni, D., Wang, J. & Xie, D. (2024) Apoptosis and cuproptosis Co-activated Copper-based metal-organic frameworks for cancer therapy, J Nanobiotechnology. 22, 546.Zhong, Y., Cai, C., Chen, T., Gui, H., Chen, C., Deng, J., Yang, M., Yu, B., Song, Y., Wang, T., Chen, Y., Shi, H., 6.Xie, D., Chen, C. & She, Y. (2024) PET/CT-based deep learning grading signature to optimize surgical decisions for clinical stage I invasive lung adenocarcinoma and biologic basis under its prediction: a multicenter study, Eur J Nucl Med Mol Imaging. 51, 521-534.7. She, Y., Li, S., Deng, J., Ren, Y., Zhao, M., Zhong, Y., He, Y., Chen, Q., Zhao, D., Zhu, Y., Hou, L., Wu, C., Xie, D. & Chen, C. (2022) Clinicopathologic characteristics and prognostic impact of atypical EGFR mutations in completely resected lung adenocarcinoma, Eur J Cancer. 177, 53-62.8. Hao, B. B., Ma, K., Xu, J. Y., Fan, R. F., Zhao, W. S., Jia, X. L., Zhai, L. H., Lee, S., Xie, D. & Tan, M. J. (2024) Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations, Acta Pharmacol Sin. 45, 1305-1315.9. Shi, Y., Li, C., Zhang, X., Peng, C., Sun, P., Zhang, Q., Wu, L., Ding, Y., Xie, D., Xu, Z. & Zhu, W. (2024) D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer, Brief Bioinform. 25.10. Lin, J. W., Zhou, Y., Xiao, H. P., Wu, L. L., Li, P. C., Huang, M. D., Xie, D., Xu, P., Li, X. X. & Li, Z. X. (2024) Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis, Chemical Science.11. Yang, M. L., Sun, W. Y., Wang, L., Tang, H., Xu, X., Yang, L. W., Ni, J. J., Zheng, K. E., Jiang, X., Xu, W. W., Zhao, G. F., She, Y. L., Zhang, L., Xie, D. & Chen, C. (2022) Curcumin loaded polycaprolactone scaffold capable of anti-inflammation to enhance tracheal cartilage regeneration, Materials & Design. 224.12. Xie, D., Deng, J., Gonzalez-Rivas, D., Zhu, Y., Jiang, L., Jiang, G. & Chen, C. (2021) Comparison of video-assisted thoracoscopic surgery with thoracotomy in bronchial sleeve lobectomy for centrally located non-small cell lung cancer, J Thorac Cardiovasc Surg. 161, 403-413.e2.13. Wu, L. L., Qiu, L. H., Chen, X., Yu, W. J., Li, C. W., Qian, J. Y., Liang, S. H., Lin, P., Long, H., Zhang, L. J., Li, Z. X., Li, K., Jiang, F., Ma, G. W. & Xie, D. (2023) Reconsidering N component of cancer staging for T1-2N0-2M0 small-cell lung cancer: a retrospective study based on multicenter cohort, Respir Res. 24, 168.14. Qian, J. Y., Hao, Y., Yu, H. H., Wu, L. L., Liu, Z. Y., Peng, Q., Li, Z. X., Li, K., Liu, Y., Wang, R. R. & Xie, D. (2023) A Novel Systematic Oxidative Stress Score Predicts the Survival of Patients with Early-Stage Lung Adenocarcinoma, Cancers (Basel). 15.15. Wu, L. L., Qian, J. Y., Li, C. W., Zhang, Y., Lin, W. K., Li, K., Li, Z. X. & Xie, D. (2022) The Clinical and Prognostic Characteristics of Primary Salivary Gland-Type Carcinoma in the Lung: A Population-Based Study, Cancers (Basel). 14.16. Wu, L. L., Chen, W. T., Li, C. W., Song, S. H., Xu, S. Q., Wan, S. P., Liu, Z. Y., Lin, W. K., Li, K., Li, Z. X. & Xie, D. (2022) The Construction and Validation of Nomogram to Predict the Prognosis with Small-Cell Lung Cancer Followed Surgery, Cancers (Basel). 14.17. Gao, J., Zhang, L., Li, Z., Wang, F., Qiu, L., Dou, X., Li, C., Zhu, Y., Ma, G., Jiang, G., Xie, D. & Chen, C. (2021) UniPortal thoracoscopic pneumonectomy does not compromise perioperative and long-term survival in patients with NSCLC: A retrospective, multicenter, and propensity score matching study, Lung Cancer. 159, 135-144.18. Deng, J., Zhao, M., Wang, T., She, Y., Wu, J., E, H., Gao, J., Sun, X., Jiang, G., Zhu, Y., Xie, D. & Chen, C. (2020) A modified T categorization for part-solid lesions in Chinese patients with clinical stage I Non-small cell lung cancer, Lung Cancer. 145, 33-39.19. Deng, J., She, Y., Yang, M., Zhang, L., Xie, D. & Chen, C. (2020) Radiomics: a potential biomarker for N2 malignancy in clinical stage I lung adenocarcinoma, Transl Lung Cancer Res. 9, 1623-1624.20. Xie, D., Wang, T. T., Huang, S. J., Deng, J. J., Ren, Y. J., Yang, Y., Wu, J. Q., Zhang, L., Fei, K., Sun, X. W., She, Y. L. & Chen, C. (2020) Radiomics nomogram for prediction disease-free survival and adjuvant chemotherapy benefits in patients with resected stage I lung adenocarcinoma, Transl Lung Cancer Res. 9, 1112-1123.21. Yang, M., She, Y., Deng, J., Wang, T., Ren, Y., Su, H., Wu, J., Sun, X., Jiang, G., Fei, K., Zhang, L., Xie, D. & Chen, C. (2019) CT-based radiomics signature for the stratification of N2 disease risk in clinical stage I lung adenocarcinoma, Transl Lung Cancer Res. 8, 876-885.22.Shen Y, Yu N, Zhao W, Niu S, Qiu P, Zeng H, Chen Z, Men W, Xie D.M1-macrophage membrane-camouflaged nanoframeworks activate multiple immunity via calcium overload and photo-sonosensitization.Biomaterials,2025,DOI: 10.1016/j.biomaterials.2025.123287.23.Lin W, Tang H, Cao R, Chen J, Wang L, She Y, Zhang L, Chen Y, Pan Z, Bai Q, Zhao D, Yang M, Zhao G, Sun W, Xie D, Chen C.3D-printed Engineered Trachea Functionalized by Diverse Extracellular Matrix Particles.Adv Healthc Mater,2025,DOI: 10.1002/adhm.202500124.24.Yi C, Bian D, Wang J, Hu S, Sun L, Yan Y, Wang S, Shen Z, Yu H, Yang Y, Zhou Y, Liu X, Song N, Zhu Y, Zhao D, Jiang G, Duan L, He W, Xie D, Dai J, Zhang L, Zhang P.: Anti-PD1 based precision induction therapy in unresectable stage III non-small cell lung cancer: a phase II umbrella clinical trial. Nat Commun 2025, 16(1):1932.25.Wen M, Qiu P, Meng J, Zhao W, Wang X, Niu S, Tao C, Yu N, Chen Z, Xie D: Multifunctional nanozymes for sonodynamic-enhanced immune checkpoint blockade therapy by inactivating PI3K/AKT signal pathway. Biomaterials 2025, 318:123125.26.Zhou LQ, Li K, Liu YY, Zhang RJ, Yao YC, Chen QQ, Xie D, Zhang XJ: Living Cell-Derived Intelligent Nanobots for Precision Oncotherapy. Advanced Functional Materials 2024, 34(10).27.Zhong Y, Cai C, Chen T, Gui H, Chen C, Deng J, Yang M, Yu B, Song Y, Wang T et al: PET/CT-based deep learning grading signature to optimize surgical decisions for clinical stage I invasive lung adenocarcinoma and biologic basis under its prediction: a multicenter study. Eur J Nucl Med Mol Imaging 2024, 51(2):521-534.28.Lin JW, Zhou Y, Xiao HP, Wu LL, Li PC, Huang MD, Xie D, Xu P, Li XX, Li ZX: Antitumor effects of a Sb-rich polyoxometalate on non-small-cell lung cancer by inducing ferroptosis and apoptosis. Chem Sci 2024, 15(37):15367-15376.部分中文文章：1.謝冬,陳昶，王海峰，等. 閉合性氣管支氣管損傷15例. 中華胸心血管外科雜志,2016,32(2)94-98.2. 包敏偉,謝冬,費苛，姜格寧，等. 116例胸腺囊腫的外科治療. 中華胸心血管外科雜志,2016,32(1):14-17.3. 謝冬, 包敏偉,謝惠康，等.113例縱隔畸胎瘤的外科治療. 中華胸心血管外科雜志,2016，32(3)：132-135.4. 周琪,謝冬,費苛,姜格寧. 心包切開術后綜合征診治進展.中國胸心血管外科臨床雜志. 2017, 24(4): 306-309.5.謝冬,陳昶,朱余明,姜格寧.單孔胸腔鏡手術的現(xiàn)狀與展望.中華腔鏡外科雜志,2016,9(2):4-7.6.謝冬,陳昶,姜格寧. 肺癌外科手術切口的演變與發(fā)展趨勢,中國肺癌雜志, ,2016,(6):343-346.7. 謝冬,戴潔,楊平,姜格寧.肺癌精準外科發(fā)展現(xiàn)狀與展望, 中華實驗外科雜志,2016,(8):1889-1892.8. 厲逑元, 謝冬, 姜格寧.普胸外科手術風險預測模型的現(xiàn)狀與進展,中華胸心血管外科雜志，2016,(9):561-564,568.9.謝冬, 姜格寧. 胸鎖關節(jié)感染的外科治療，中華胸心血管外科雜志,2016,, 32(8):506-508.10.謝冬,金宇星,王海峰等. 59例支氣管結石病的外科治療. 中華胸心血管外科雜志,2015,31(4):217-220.11. 謝冬, 姜格寧，趙德平，等. 單孔全胸腔鏡治療中央型肺部腫瘤5例. 中華胸心血管外科雜志, 2015,31(3):177-178.12.謝冬,尤小芳,謝惠康,陳曉峰,徐志飛,姜格寧, 陳昶,周曉,丁嘉安. 18例支氣管內型錯構瘤的臨床分析. 中華胸心血管外科雜志,2012,28(3):167-168.13. 謝冬,姜格寧,徐志飛等.插管后氣管狹窄的外科治療進展. 中華胸心血管外科雜志, 2013, 29(3):180-182.14.謝冬,姜格寧,費苛,等. 肺切除術后支氣管胸膜瘺的治療進展. 中華胸心血管外科雜志, 2013, 29(8):502-504.15.謝冬,姜格寧,陳曉峰，等.114例肺隔離癥的外科治療. 中華外科雜志, 2013，51(9):861-862.16. 謝冬,費苛,姜格寧，等. 不切除肺的支氣管節(jié)段切除術23例報道. 中華外科雜志, 2013，51(10):942-944.